Evaluation and management of acute and recurrent UTIs

Dr. Suzette Sutherland shares her clinical strategy on the latest in UTI evaluation and management as incidence of drug resistant pathogens continues to rise and there are limited new antibiotics, creating a perfect storm for antibiotic resistance.

For the first time,the guidelines from the American Urological Association discuss cranberry prophylaxis for women with rUTIs.

That has been a significant part of my protocol, a medical-grade supplement that contains cranberry proanthocyanidins (PAC), specifically 36mg of soluble A-type PAC. I have never had a patient unable to tolerate the PAC approach.

Nazia Q. Bandukwala, DO - Female and Reconstructive Urologist, PPG Urology Specialists Atlanta (Piedmont Hospital Network), Atlanta, GA


The soluble PAC in ellura have unmatched potency to help break the cycle of recurrent UTIs.

It all starts with proanthocyanidins (PACs), a natural ingredient found in cranberries. In the right concentration soluble PACs, which are rapidly bioavailable and bioactive, are proven to provide high levels of anti-adhesion activity, preventing UTI-causing bacteria from sticking to the urinary tract wall.

  • Anti-Adhesion Activity is the soluble PACs ability to bind the P-fimbriae of uropathogenic bacterium inhibiting them from attachment, the initial step of a UTI.1

Not all cranberry supplements are created equal.

ellura is made using a proprietary process that allows us to access potent, bioactive PACs, giving your patients the highest levels of anti-adhesion activity and stopping rUTIs before they start.

  • It is an essential distinction that this insoluble PAC does not prevent bacterial adhesion to the bladder. Insoluble PACs have greatly reduced bioavailability as they are bound by cellulose, pectin, and hemicellulose found in the residual skins, seeds, flesh and stems of the cranberry.1
ellura Mechanism of Action

Reasons to believeSTUDIES

  1. Catheter-Associated Urinary Tract Infections

    Does cranberry have a role in catheter-associated urinary tract infections?

  2. Target Dose for UTI Prevention

    36mg/72mg PAC identified and confirmed as target dose for UTI prevention

  3. Asymptomatic Bacteriuria After Cystoplasty

    Effectiveness of a cranberry (Vaccinium macrocarpon) preparation in reducing asymptomatic bacteriuria in patients with an ileal enterocystoplasty

  4. Prophylaxis of rUTIs compared with antibiotic

    Cranberry syrup vs. trimethoprim in the prophylaxis of recurrent urinary tract infections among children: a controlled trial

additional studies


  1. AUA Guidelines

    Antimicrobial resistance is one factor that has led to an increasing interest in the scientific community to study non-antibiotic modalities in the prevention of rUTI, including the use of probiotics and the consumption of cranberry products.

  2. Non-Antibiotic Prevention

    As a doctor, you may be prescribing a daily antibiotic to treat UTIs, but also as preventive therapy for recurrent infections. Multiple studies demonstrate that poor compliance, along with repeated antibiotic use leads to resistance and, therefore, makes it harder to prevent infection.

    In early 2015 the World Health Organization endorsed a global action plan to tackle antibiotic resistance, the most urgent drug resistance trend compromising your ability to treat infectious disease.¹ On top of bacterial resistance, unwanted side effects of antibiotics beg a new solution for managing recurrent UTIs.

    Now, you can feel confident in recommending ellura, a medical-grade, non-antibiotic alternative for preventing UTIs. ellura is a dietary supplement that contains a natural ingredient and has gone through complex extraction and extensive testing to harness the power of its bioactive ingredient, PAC (proanthocyanidins), to work on the offense, trapping and flushing out harmful bacteria before they can make themselves at home.

    We recommend your patients take ellura with an antibiotic at the onset of infection and then continue taking ellura once daily to keep their urinary tract in check and to constantly flush out bad bacteria that could lead to future UTIs.


Listen to key opinion leaders about the importance of non-antibiotic rUTI prevention and the power of cranberry PAC.

Dr. Howell describes the action of proanthocyanidins preventing bacterial adhesion
Dr. Fletcher advocates patient self care for bladder and vaginal health
Dr. Cohen discusses getting UTI patients off antibiotic therapy
Dr. Brian Flynn – Antibiotic Stewardship and UTIs


We’re here to support you, with resources to help your patients better understand rUTIs and how ellura can help. Review the links below for important tools to help you discuss your patients’ care.


    Help your patients understand how bacteria attaches in the bladder and how the PAC in ellura s helps stop this first step of infection with this visual tool.


    Use this helpful step-by-step guide to communicate how ellura works, along with dosing and ordering getting a new patient established with ellura and set up for success.


    Help new patients access the biggest discount available by submitting this form to our Customer Care Team. We’ll reach out, answer their questions and help them order.



Complete this secure form to reach out and request more information.

A member of our team would be happy to connect with you and share more resources on how ellura can help prevent infection in rUTI patients.

You can request a patient material kit that will include:

  • Patient brochures
  • UTI cards
  • Starter capsules (Note: the active ingredient offers 24-hour anti-adhesion protection of the urinary tract wall and must be taken daily, these 2 starter capsules are a reminder to patients to order and are not sufficient for ongoing UTI protection.)
  • Referral forms


Kevin Wade
Executive Vice President of Clinical and Physician Development
With over 23 years of pharmaceutical knowledge and industry experience Kevin is driven to raise and set new standards for supplement proof of safety and efficacy. Every day, he works for our mission and commitment to your patients: to offer proven non-prescription products that are supported by unsurpassed science, education, and customer care. Just as he dives all in to delivering the best work, his family is of the utmost importance. He is also passionate about bold red wines and travel experiences that allow you to explore and truly experience the world.
Kristi Johnson
Director of Sales
Kristi Johnson joined the team at the beginning of this year. Kristi comes to us with 14 years of sales experience with technology companies. For the last 9 years she has worked for Philips within the Population Health Management group and helping the business grow through the development and implementation of strategic solutions. She is excited for what lies ahead with ellura and has already enjoyed working directly with many healthcare providers. Kristi and her husband Eric have two lovely daughters and a pup named Sadie. She loves spending time with family and friends, especially when there is food, wine or anything outdoors involved!
Aspen Bunyak
Senior Manager, Strategic Partnerships, Healthcare
Aspen Bunyak has over 9 years of experience in the healthcare space and a passion to connect with healthcare providers, whether it’s via email or at the many conferences all over the US throughout the years. She recently completed her MBA and has been with Trophikos for 6 years. You have a question? She’ll have an answer and if not, she will help you find it! Aspen also loves fitness, wine, all things food and her two amazing dogs: Rocky and Tumtum.
Peyton Carell
Sales Development Representative
Peyton Carell is the latest addition to the ellura sales team! Prior to her new role, she spent almost 3 years with the ellura Customer Care Team. This experience has enabled her to get to intimately know the needs and concerns of your patients with rUTIs. This foundation has made Peyton passionate about ellura and the life changing impact. Originally from Nashville, she graduated from Auburn University and moved to Atlanta when she started working at Trophikos. She is the proud momma of a sweet golden retriever named Doug who is very popular at the office.
  1. Howell AB et al. “A-type cranberry proanthocyanidins and uropathogenic bacterial anti-adhesion activity.” Phytochemistry, 66, no. 18 (September 2005): 2281-2291